Brief course description
This course covers basic cell biology, fundamental genetic engineering, cell culture, bioreactor design, downstream bioprocesses and applications of biotechnology. In the end of the semester, the students are grouped to design and present the production process of some products, starting from market research, genetic engineering of the cells, production process (including bioreactor design and operation) and downstream purification process.
Course keywords
基因工程 (genetic engineering), 細胞培養 (cell culture and fermentation), 下游程序工程(downstream process), 生質化學品 (bio-derived chemicals), 生技產業(biotechnology industry)
Syllabus
Basics:
Chap 1 Overview of Biotechnology
Chap 2 Overview of Biological Systems
Chap 3 Growth and metabolism
Chap 4 Genetic Engineering-Procaryote
Chap 5 Genetic Engineering-Yeast and Fungi
Chap 6 Culture of Animal Cells
Chap 7 Microbial Process Kinetics
Chap 8 Bioreactor
Chap 9 Downstream Process
Applications:
Chap 10 Bio-based Production of Chemicals
Chap 11 Antibiotics
Chap 12 Amino Acids
Chap 13 Organic Acids
Chap 14 Microbial Polyhydroxyalkanoates, Polysaccharides and Lipids